Zucara Therapeutics Inc.

Zucara is developing the first medicine to prevent potentially fatal low blood sugar episodes in Type 1 diabetes, an untreated problem for over 20 M patients.

  • Stage Product In Development
  • Industry Healthcare Services
  • Location Vancouver, BC, Canada
  • Currency CAD
  • Founded December 2014
  • Employees 0
  • Website zucara.ca

Company Summary

Zucara is developing a novel, breakthrough drug for the treatment of dangerously low blood sugar, or hypoglycemia, associated with insulin therapy. We are initially targeting patients with Type 1 diabetes (T1D) who have a history of severe, recurrent hypoglycemia (approximately 2 million patients worldwide). Opportunities also exist to expand the market into T1D patients with mild to moderate hypoglycemia and insulin-dependent Type 2 diabetes patients. The total hypoglycemia market includes over 50 million patients worldwide, valued at over $8 Billion.

Zucara is currently completing experiments to optimize a final product to advance through first-in-human proof of concept studies. We anticipate that generation of human proof of concept data (beginning 2017) will generate significant value for the company, and enable acquisition of the technology by a pharma partner in the diabetes market that will complete a registration trial and gain regulatory approval for the product.

Zucara is operating in a capital efficient manner, as a virtual company, with company management and leadership of product development provided by its founders, The Centre for Drug Research and Development (CDRD) and MaRS Innovation.

Team

  • Richard is the Head of Analytical Chemistry at The Centre for Drug Research and Development (CDRD). With over 15 years of drug development experience (formerly at Angiotech Pharmaceuticals), Richard has developed intellectual property in diverse technology areas with over 70 patents and applications filed in 12 patent families (5 issued). He has completed formulation development for multiple pre-clinical & clinical stage drugs & medical devices.

  • Dominic is the Director, Technology & Venture Development at MaRS Innovation. He holds a PhD (Biological Chemistry) from University of Toronto and an MBA from the Rotman School of Management, at the University of Toronto. He has over 10 years experience in biotech and finance, including venture capital, business development and R&D. Dominic was previously a director at BDC Venture Capital and a scientist at Diversa Corporation.

  • Jon Jafari
    CBO

    Jon is Sr. Director, Business Development at CDRD, and was previously at QLT Inc and Eli Lilly, with responsibilities for new product planning, market research and licensing activities. Jon also had research roles at Indiana University and Genetic Therapy Inc. He received a BS Biology and MBA from Indiana University and his MS Biotechnology from Johns Hopkins University.

  • Co-founder and Chair, Scientific Advisory Board

    Michael is a Professor in the School of Kinesiology & Health Science at York University and a Sr. Scientist at LMC Diabetes & Endocrinology, with a PhD in Medical Sciences from McMaster University. Researching hormonal responses to exercise and stress in diabetes, Michael is an expert on exercise and hypoglycemia prevention in type 1 diabetes, and a contributing author to multiple Canadian and international clinical practice guidelines.

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