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Thetis Pharmaceuticals LLC

Leveraging existing active pharmaceutical ingredients to chemically create new molecular entities with enhanced PK and efficacy

  • Stage Product In Development
  • Industry Biotechnology
  • Location Fairfield, CT, USA
  • Currency USD
  • Founded January 2011
  • Employees 3
  • Website

Company Summary

Founded in January 2011, Thetis is an emerging pharmaceutical company developing a portfolio of prescription drugs for the treatment of type 2 diabetes, hypertriglyceridemia and dyslipidemia. All have blockbuster potential as first-in-class or best-in-class opportunities in major pharmaceutical markets. EPA, a principal active ingredient in omega-3 fatty acids, is uniquely incorporated into the chemical structures of the Thetis compounds.


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    Frank Sciavolino, PhD
    Chief Scientific Officer

    Dr. Sciavolino has more than 40 years experience in the pharmaceutical industry. At Pfizer, he was the enabling force behind Zithromax and the Cox-2 Alliance with Pharmacia. Dr. Sciavolino has holds over 30 patents. He has a PhD in organic chemistry from the University of Michigan and BS in Pharmacy from St. John's University.

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    Banavara L. Mylaria, PhD
    Chief Technology Officer

    Dr. Mylari has over 40 years experience in the pharmaceutical industry. At Pfizer he worked on a number of successful projects in diabetes, antibacterials, antiprotozoals, and anti-inflammatory drugs. He played a key role in the commercialization of salinomycin, and a lead role in the development of zopolrestat for diabetic complications. Dr. Mylari obtained his PhD in organic chemistry from Indiana University, and holds over 50 US patents.

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    G. Alexander (Zan) Fleming, MD
    Senior Medical Advisor

    Dr. Fleming has extensive FDA regulatory experience. He had responsibility at the FDA for the review of new drug applications (NDAs) in the areas of metabolic and endocrine disorders, and lipid-lowering agents. He is Board Certified in Internal Medicine, and Endocrinology and Metabolism. Dr. Fleming is a member of numerous scientific advisory boards and expert committees and is a Founder, President/CEO of the consulting firm, Kinexum.

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    Gary Mathias
    Chief Financial Officer

    Mr. Mathias has been involved in the healthcare arena as an entrepreneur, investor and banker for 25 years. He is managing director of Carter Morse & Mathias (an investment banking firm) and previously was SVP in the Healthcare Group of GE Equity and chief operating officer of Diabetes Support Systems. Mr. Mathias has a BA in Economics from Harvard College and MBA from the Yale School of Management.


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    Lathrop & Gage (IP)
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    JH Cohn LLP

Previous Investors

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    Connecticut Innovations
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    Stonehenge Growth Capital
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    River Valley Investors