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Prime Synthesis, Inc.

Prime Synthesis, Inc. has developed a proprietary technology to lower manufacturing costs for cutting-edge DNA and antibody-based drugs.

  • Stage $3M in TTM Revenue
  • Industry Biotechnology
  • Location Aston, PA, USA
  • Currency USD
  • Founded May 1989
  • Employees 15
  • Website

Company Summary

Prime Synthesis,Inc. manufactures and sells a key raw material that is used for making synthetic DNA and purifying antibodies. Its customers include most major pharmaceutical companies and a number of specialty biopharma firms. Over 200 synthetic DNA/RNA drugs are currently in clinical trials and many block buster antibody drugs are on the market.
A next generation product has been developed to reduce the manufacturing costs of these drugs.


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    David H. Eyler

    Employment History

    1990- Present CEO – Prime Synthesis, Inc
    • Production and sales of products into the DNA synthesis market.

    1988-90 Business Development VP – CPG, Inc. Fairfield, New Jersey
    • Business plan and implementation for products into new DNA synthesis market.

    1983-88 Business Development VP – Rockland Medilabs, Valley Cottage, NY
    • Market development for new clinical tests.

    1981-83 Business Development VP-China & USSR–

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    Marc L. Rothstein

    Temple University B.S. 1974 Chemistry
    Temple University M.S. 1978 Electrochemistry
    Wharton School of Business: MBA Coursework 1990-1993 Marketing

    Positions and Honors
    Positions and Employment

    1974-1979 Research Scientist- Leeds and Northrup Company

    1979-1983 Applications Scientist- Electroche

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    Dianne M. Rothstein
    VP of Research


    Drexel University, Philadelphia, PA: Ph.D. Materials Engineering, December, 2007
    Drexel University, Philadelphia, PA : MS Chemistry, June, 1984
    Indiana University of Pennsylvania, Indiana, PA: BS Biology, June, 1975
    Temple University, Ambler PA 9 MBA credits, 1979
    Virginia Polytech Institute, Blacksburg, VA: ACS course “Polymer Chemistry, Prin


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    ReedSmith LLP
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    J. Sacchetta, CPA

Previous Investors

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    Ben Franklin Technology Partners (2 rounds), Dept. Commerce (MATAAC)
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    National Institutes of Health (SBIR Grant),
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    Internal Revenue Service (Qualifying Therapeutic Discovery Grant)