Pacylex Pharmaceuticals, Inc.

Pacylex is developing a new, oral, first-in-class cancer treatment based on newly discovered driver biology in leukaemia, lymphoma and solid tumors.

  • Stage Product In Development
  • Industry Biotechnology
  • Location Edmonton, AB, Canada
  • Currency CAD
  • Founded July 2012
  • Employees 6
  • Incorporation Type Other
  • Website pacylex.com

Company Summary

Pacylex is a clinical stage Canadian oncology company exploiting a new discovery in cancer biology with a first in class, small, oral chemotherapeutic, PCLX-001, to turn on cell death only in cancer cells. Phase 1 studies are ongoing at several Canadian sites.

Team

  • President and CEO

    Michael is a 26 year biotech veteran, CEO of Sonescence & SEA Medical Systems, CBO of Strategent, Corium, & Therashock, VP at SciDose & Auspex, & Senior Program Executive at Nektar & Ligand. He raised Seed through Series C and established partnerships worth >$175 Million. Michael led oncology product development including during the Phase III/NDA for Targretin, and business planning for drug delivery of Leuprolide, Paclitaxel and Irinotecan.

  • Co-founder and COO

    Ryan has a diverse background in research, technology commercialization, business development, and financing early stage companies. Ryan provided business planning and company development for many early-stage, technology-based ventures in health-related fields at TEC Edmonton and as an independent consultant. Additionally, he has helped multiple Alberta companies in obtaining financing in his role with the angel investing network, TEC VA.

  • Co-founder and CSO

    Luc is a professor of cell biology at University of Alberta with 21 years of experience studying protein fatty acylation. He received his PhD from the Université de Sherbrooke and completed his Post-Doctoral Fellowship at the Memorial Sloan-Kettering Cancer Centre. He has more than 40 publications and 3 patents published or pending. Luc is also the founder and president of Eusera, an antibody manufacturing company in Edmonton, AB.

  • Co-founder and CMO

    John is a medical oncologist and Director, Clinical Trials Unit at the Cross Cancer Institute, Professor of Oncology, University of Alberta, and Chair of the Alberta Pre-Phase I Cancer Program (www.prephaseone.com). As Executive Director of Translational Research In Oncology (TRIO), a global clinical trial company, he has access to clinical trial operations and samples to facilitate the clinical evaluation of diagnostic and therapeutic agents.

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