Metaphason Inc.

Metaphason is developing a safe, scalable, and commercially viable platform technology for the oral delivery of insulin and other biologics using probiotics.

  • Stage Concept Only
  • Industry Biotechnology
  • Location Vienna, VA, USA
  • Currency USD
  • Founded September 2017
  • Employees 3
  • Incorporation Type C-corp

Company Summary

Oral delivery of biologics (such as insulin and antibodies) has been challenging
because of the harsh proteolytic environment of the stomach, along with limited
permeability across the intestinal membrane, causing the biologic to degrade
before reaching the bloodstream. We are developing a safe, scalable, and commercially viable platform technology to deliver insulin and other biologics orally by packaging them into probiotics.

Team

  • Co-Founder and Chief Executive Officer (CEO)

    Dr. Manu Kohli has over a decade of biotech/pharmaceutical experience leading senior teams in drug discovery, drug delivery, and biologics development, and has many patented technologies in genetic engineering and biologics. He obtained his Ph.D. from Georgetown University with Dr. Timothy Jorgensen followed by a postdoctoral fellowship with renowned cancer researcher and Breakthrough Prize winner Dr. Bert Vogelstein at Johns Hopkins University.

  • Marcelo Reis
    Co-Founder and Chief Scientific Officer (CSO)

    Dr. Marcelo Reis obtained his M.D./Ph.D. degree in Chemical Biology from the Federal University of Rio de Janeiro, Brazil, followed by a postdoc at Johns Hopkins University with Dr. Bert Vogelstein. Earlier, he was Head of the Division of Pharmacology at The Brazilian National Cancer Institute. He was VP of Business Development in Latin America for Personal Genome Diagnostics, and is faculty at The D’Or Institute for Research and Education.

  • Gregory Riggins
    Co-Founder and Scientific Advisor

    Dr. Riggins received his M.D. and Ph.D. degrees from Emory University, and is Professor of Neurosurgery and Oncology at Johns Hopkins University. In addition, he directs the Brain Cancer Biology and Therapy Research Laboratory. His laboratory has identified new therapies for glioblastoma and medulloblastoma, and several of these therapies have advanced
    to new clinical trials.

Advisors

  • Chris Sorensen
    Unconfirmed

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