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Intelligent Substrates Inc.

ISI designs information-rich microenvironments for cell culture applications, such as stem cell & tissue engineering, and cell-based assays.

  • Stage Prototype Ready
  • Industry Biotechnology
  • Location Baltimore, MD, USA
  • Currency USD
  • Founded March 2007
  • Employees 3
  • Website

Company Summary

Intelligent Substrates develops innovative microenvironments for in vitro cell culture research, tissue engineering, and drug discovery. A cell's environment is second only to its DNA in terms of impact on function and health. ISI's initial products, protein micropatterned substrates for cell-based applications, are targeted to strategic partners in the rapidly growing cell-based assay market and pharma, biotech and academic scientists worldwide.


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    Will Heinz
    President and CEO

    Dr. Heinz trained in biophysics at Johns Hopkins University and did postdoctoral work in single molecule microscopy in the Laser Applications Group at NIST, after which he returned to Hopkins to work on protein patterning related projects. He has an exceptionally strong background in biophysics and optics, and experience working with patterned substrates and cell culture. He is a co-inventor of the patented patterning approach.

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    Bill Sharp
    Business Advisor

    Mr. Sharp's 30-year career spans private venture-backed businesses, mid-size and Fortune 100 public companies in the life science tools and services, diagnostics, and medical device markets. He has unique insight into the market challenges and opportunities for ISI. He has raised over $35M in VC investment, played a key role in the sale of 3 firms, and commercialized over 500 products and services.


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    George Cox, Ph.D., Esq., IP & Business Law Counseling, LLC
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    Bill Williams, Stegman & Co.

Previous Investors

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    Eric and Loreen Heinz
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    Eric Hoh
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    Jeffrey Lawson