This disruptive innovation is an application of Physical Biology. A patent (EP 13176364) protects the modification of the cancerous phenotype of a tissue by mechanical signals. Magnetizable particles are positionned around (Not in) a tumor and submitted to a gradient of magnetic field. Proof of Concept in vivo obtained in 2012. The concept in vitro 3D is validated in the literature (M Paszek 2005, F Montel 2011).