Califia is developing novel drugs active against drug resistant cancers unresponsive to current therapies, while displaying minimal toxicity in humans.
Califia is developing drugs for treating TCR-deficient solid tumors (ovarian, endometrial, prostate, liver, etc). Recent clinical trials of the 1st gen TCR drug validates our approach. Califia is poised to improve on success with a 2nd gen drug (CAP-0121) displaying superior PK/stability/efficacy that is combined with a molecular-based companion diagnostic to identify patients whose cancers are TCR deficient.