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Bio3 Research srl

Patented use of HMGB1 protein for cardiovascular disease and connective tissue regeneration. Key role of HMGB1 confirmed in patients.

  • Stage Product In Development
  • Industry Biotechnology
  • Location Waltham, MA, USA
  • Currency USD
  • Website

Company Summary

Bio3 has 15 patents on the use of the protein HMGB1 for (a) connective tissue regeneration (diabetic foot ulcers, wound healing, cartilage repair and bone regeneration), and (b) treatment of cardiovascular disorders (atherosclerosis, restenosis, arterial stenosis, and vasculitis). Bio3’s products target significant markets with unmet needs. Bio3’s dietary supplement, Biocysan, treats anemia and oxidative stress in chronic kidney disease patients.


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    Francesco Paolo Pilato

    Dr. Pilato, educated as a chemist, served for more than thirty years at the top executive level in the pharmaceutical and diagnostic industry. Much of his professional experience was in the international arena.

    In the seventies, after a short experience at Lederle Labs, he was appointed Resident Area Manager Middle East at Farmitalia. Later he moved to Japan as Assistant to the Managing Director of Nippon Farmitalia. After his return to Farmit


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    Bruce M. Landay [Landay Leblang Stern]